Pregnant women's and policymakers' preferences for the expansion of noninvasive prenatal screening: A discrete choice experiment approach study.

Nguyen HM, Baradaran M, Daigle G, Nshimyumukiza L, Guertin JR, Reinharz D. Health Sci Rep. 2023;6(8):e1516. Published 2023 Aug 23. doi:10.1002/hsr2.1516. Open Access: Learn more

Tags: Patient Perspectives, Health Care Provider Perspectives, 2023, Canada, RAAs, CNVs

272 pregnant women and 24 policymakers completed the questionnaire.
In the pregnant women group, all seven attributes were statistically significant, denoting their importance, with pregnant women placing the greatest importance on cost related to the test, followed by test performance, and degree of test result certainty.
In the policymakers group, three attributes were statistically significant: test performance, degree of test result certainty regarding the severity of the disability, and cost related to the test.

Glossary

cfDNA: cell-free DNA

CMA: chromosomal microarray

CNV: copy number variation (also referred to as partial deletions/partial duplications or segmental imbalances)

CPM: confined placental mosaicism

GW: genome-wide

PPV: positive predictive value

RAA: rare autosomal aneuploidy

RAT: rare autosomal trisomy

SCA: sex chromosome aneuploidy

UPD: uniparental disomy

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Pregnant women’s and policymakers’ preferences for the expansion of noninvasive prenatal screening: A discrete choice experiment approach study.